Bioss Inc.'s Factor B Polyclonal Antibody, ALEXA FLUOR® 750 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, Immunohistochemistry, and Immunohistochemistry - fixed. The Factor B Polyclonal Antibody, ALEXA FLUOR® 750 Conjugated was generated using CFB, and Complement factor B as the antigen and it reacts with Mouse, and Rat.
Description
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes